Key Messages
- Extensively drug-resistant (XDR) Shigella cases are increasing in Los Angeles County (LAC).
 - XDR Shigella disproportionately affects men who have sex with men (MSM) and people living with HIV.
 - As Pride events begin this week, healthcare providers are asked to be vigilant for potential XDR Shigella infections and to test, treat, and report cases appropriately.
 - Due to rising antibiotic resistance, antibiotics should be reserved for patients with severe illness or underlying risk factors. Most Shigella infections are self-limiting.
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